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BDBM315269 US10172837, Methazolamide

SMILES: CC(=O)\N=c1/sc(nn1C)S(N)(=O)=O

InChI Key: InChIKey=FLOSMHQXBMRNHR-DAXSKMNVSA-N

Data: 1 IC50

PDB links: 7 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315269   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM315269
PNG
(US10172837, Methazolamide)
Show SMILES CC(=O)\N=c1/sc(nn1C)S(N)(=O)=O
Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
PDB
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



Naia Metabolic, Inc.

US Patent


Assay Description
Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...


US Patent US10172837 (2019)


BindingDB Entry DOI: 10.7270/Q2VT1V5M
More data for this
Ligand-Target Pair