BDBM31530 2-methyl-5-[(methylamino)methyl]-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide (I-2)::Substituted Benzamide Derivative, 49::med.21724, Compound 164

SMILES CNCc1ccc(C)c(c1)C(=O)N[C@H](C)c1cccc2ccccc12

InChI Key InChIKey=SIBDAZDNSVDATL-MRXNPFEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31530   

TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31530(2-methyl-5-[(methylamino)methyl]-N-[(1R)-1-(naphth...)
Affinity DataIC50:  1.30E+3nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
University Of Bonn

LigandPNGBDBM31530(2-methyl-5-[(methylamino)methyl]-N-[(1R)-1-(naphth...)
Affinity DataIC50:  1.23E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31530(2-methyl-5-[(methylamino)methyl]-N-[(1R)-1-(naphth...)
Affinity DataIC50:  1.18E+3nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed