BDBM32194 3-cyano-4-fluoranyl-N-[4-fluoranyl-3-(5-oxidanyl-1,3-benzodioxol-4-yl)phenyl]benzenesulfonamide::3-cyano-4-fluoro-N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phenyl]benzenesulfonamide::TG1-268-1::cid_16072278

SMILES Oc1ccc2OCOc2c1-c1cc(NS(=O)(=O)c2ccc(F)c(c2)C#N)ccc1F

InChI Key InChIKey=WXAGWZYGCQDYDM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32194   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32194(3-cyano-4-fluoranyl-N-[4-fluoranyl-3-(5-oxidanyl-1...)
Affinity DataIC50:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM32194(3-cyano-4-fluoranyl-N-[4-fluoranyl-3-(5-oxidanyl-1...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32194(3-cyano-4-fluoranyl-N-[4-fluoranyl-3-(5-oxidanyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay