BDBM32909 (4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-carboxylate::(4-methyl-2-oxochromen-7-yl) furan-2-carboxylate::2-furancarboxylic acid (4-methyl-2-oxo-1-benzopyran-7-yl) ester::MLS000712758::SMR000282525::US11584714, Compound 12#::cid_728528::furan-2-carboxylic acid (2-keto-4-methyl-chromen-7-yl) ester

SMILES Cc1cc(=O)oc2cc(OC(=O)c3ccco3)ccc12

InChI Key InChIKey=WVAYNWNBGPUATF-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32909   

TargetMannan-binding lectin serine protease 2(Homo sapiens)
Omeros

US Patent
LigandPNGBDBM32909((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Affinity DataKi: <1.00E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Omeros

US Patent
LigandPNGBDBM32909((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Affinity DataKi: <1.00E+3nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32909((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Affinity DataIC50:  3.34E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32909((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Affinity DataIC50:  49.7nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProthrombin(Homo sapiens (Human))
Omeros

US Patent
LigandPNGBDBM32909((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Affinity DataIC50:  949nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32909((4-methyl-2-oxidanylidene-chromen-7-yl) furan-2-ca...)
Affinity DataIC50: >5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay