BDBM330389 US9725436, Entry 8
SMILES CC(C)S(=O)(=O)N1CCN(CC1)c1ccc(\C=C\c2cc(Cl)cc(c2)-c2ccncc2)cc1
InChI Key InChIKey=JMAIZXLLNFXDDS-ONEGZZNKSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 330389
Affinity DataIC50: 5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant CYP17 (unknown origin) expressed in human AD293 cells using [21-3H]17alpha-hydroxypregnenolone as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 565nMAssay Description:Cyp21 assay protocol: AD293 cells that stably over-express recombinant CYP-21 were seeded in 96 well plates coated with poly D-lysine (10,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 58nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair