BDBM33048 (5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile::5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-2,6-diketo-4-methyl-nicotinonitrile::5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-3-pyridinecarbonitrile::5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxopyridine-3-carbonitrile::5-[4-(dimethylamino)phenyl]imino-4-methyl-2,6-bis(oxidanylidene)-1-(3-oxidanylpropyl)pyridine-3-carbonitrile::MLS000089998::SMR000024616::cid_3239318

SMILES CN(C)c1ccc(cc1)\N=C1/C(C)=C(C#N)C(=O)N(CCCO)C1=O

InChI Key InChIKey=WZQKAYDNQHZEQS-CAPFRKAQSA-N

Data  2 KI  5 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 33048   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataKi: >4.37E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataEC50:  2.82E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataEC50:  760nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataIC50:  2.58E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataIC50:  5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataIC50:  1.21E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataEC50:  890nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33048((5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydro...)
Affinity DataEC50:  550nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay