BDBM335701 (R)-6-(5-Chloroquinolin-7-yl)-3-(3-methyl-2-oxopiperidin-3-yl)pyridin-2(1H)-one::US9738626, 4 (free base and TFA salt)

SMILES C[C@@]1(CCCNC1=O)c1ccc([nH]c1=O)-c1cc(Cl)c2cccnc2c1

InChI Key InChIKey=ALGSMAYBBGCDSR-HXUWFJFHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335701   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM335701((R)-6-(5-Chloroquinolin-7-yl)-3-(3-methyl-2-oxopip...)
Affinity DataKi:  8.90nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent