BDBM33703 2-(2-Nitro-phenyl)-benzo[d][1,3]oxazin-4-one::2-(2-Nitrophenyl)-4H-3,1-benzoxazin-4-one (9)::2-(2-nitrophenyl)-3,1-benzoxazin-4-one::MLS000551096::SMR000174492::US11584714, Compound 14::cid_347675
SMILES [O-][N+](=O)c1ccccc1-c1nc2ccccc2c(=O)o1
InChI Key InChIKey=DWCFIKGNUJGZBZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 33703
Affinity DataKi: <1.00E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+3nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
Affinity DataKi: 2.24E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataIC50: >6.25E+4nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease .More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease in assay 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+4nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
Affinity DataIC50: 116nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair