BDBM34295 6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile::8-(5-methyl-2-furanyl)-3-(3-methylphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile::8-(5-methylfuran-2-yl)-3-(3-methylphenyl)-6-oxidanylidene-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile::8-(5-methylfuran-2-yl)-3-(3-methylphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile::MLS000080648::SMR000035447::cid_666162

SMILES Cc1ccc(o1)C1CC(=O)N2CN(CSC2=C1C#N)c1cccc(C)c1

InChI Key InChIKey=QYQBEBDQFITWNP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 34295   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34295(6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-te...)
Affinity DataIC50:  434nMpH: 8.0 T: 2°CAssay Description:A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...More data for this Ligand-Target Pair
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TargetEstrogen receptor(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM34295(6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-te...)
Affinity DataIC50:  3.55E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
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TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM34295(6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-te...)
Affinity DataIC50:  1.14E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
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TargetCore protein(Hepatitis C virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM34295(6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-te...)
Affinity DataIC50: >4.98E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
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TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34295(6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-te...)
Affinity DataIC50:  6.47E+3nMAssay Description:Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...More data for this Ligand-Target Pair
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TargetAmyloid-beta A4 precursor protein-binding family A member 1(Rattus norvegicus)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34295(6-keto-8-(5-methyl-2-furyl)-3-(m-tolyl)-2,4,7,8-te...)
Affinity DataIC50:  2.23E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay