BDBM347379 US10869871, ID # SW211668-(33291-R::US20230285402, ID # SW211668-(33291-R-isomer)::US9789116, SW211668
SMILES CCCC[S@@+]([O-])c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1
InChI Key InChIKey=LCYAYKSMOVLVRL-HHHXNRCGSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 347379
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 1.34nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 1.34nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 1.34nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair