BDBM347384 US10869871, ID # SW208436::US20230285402, ID # SW208436::US9789116, SW208436

SMILES CCCCS(=O)c1sc2nc(nc(-c3ccccc3)c2c1N)-c1nccs1

InChI Key InChIKey=MWJPYCGSQKOHES-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 347384   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347384(US10869871, ID # SW208436 | US20230285402, ID # SW...)
Affinity DataIC50:  1.14nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347384(US10869871, ID # SW208436 | US20230285402, ID # SW...)
Affinity DataIC50:  1.14nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347384(US10869871, ID # SW208436 | US20230285402, ID # SW...)
Affinity DataIC50:  1.14nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent