BDBM347386 US10869871, ID # SW208437::US20230285402, ID # SW208437::US9789116, SW208437

SMILES CCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1

InChI Key InChIKey=AZKMYLXTBNYBKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 347386   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347386(US10869871, ID # SW208437 | US20230285402, ID # SW...)
Affinity DataIC50:  2.05nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347386(US10869871, ID # SW208437 | US20230285402, ID # SW...)
Affinity DataIC50:  2.05nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347386(US10869871, ID # SW208437 | US20230285402, ID # SW...)
Affinity DataIC50:  2.05nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent