BDBM351918 4-Amino-6-(1-(3-(trifluoromethoxy)phenyl)-1H-indol-5-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one::US9796729, 2

SMILES Nc1ncnc2OCCN(c3ccc4n(ccc4c3)-c3cccc(OC(F)(F)F)c3)C(=O)c12

InChI Key InChIKey=QBBURCWZLKKIPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351918   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM351918(4-Amino-6-(1-(3-(trifluoromethoxy)phenyl)-1H-indol...)
Affinity DataIC50:  0.5nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent