BDBM351990 1-(2-((2S,4R)-4-fluoro- 2-(2-fluoro-3- (trifluoromethoxy) phenylcarbamoyl) pyrrolidin-1-yl)-2- oxoethyl)-5-(pyrimidin- 5-yl)-1H-indazole-3- carboxamide::US10287301, Compound 9::US10822352, Comp No. 9::US9796741, cmp No. 9

SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccc(cc12)-c1cncnc1

InChI Key InChIKey=LXCRMIOXUGVOFW-BEFAXECRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351990   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351990(1-(2-((2S,4R)-4-fluoro- 2-(2-fluoro-3- (trifluorom...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351990(1-(2-((2S,4R)-4-fluoro- 2-(2-fluoro-3- (trifluorom...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351990(1-(2-((2S,4R)-4-fluoro- 2-(2-fluoro-3- (trifluorom...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent