BDBM35245 3-(phenylsulfonyl)-1H-indole, 18g

SMILES O=S(=O)(c1c[nH]c2cccc(CCNC3CCCC3)c12)c1ccccc1

InChI Key InChIKey=HTHJJCBRKUSTFT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35245   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35245(3-(phenylsulfonyl)-1H-indole, 18g)
Affinity DataKi:  19nM IC50:  31nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35245(3-(phenylsulfonyl)-1H-indole, 18g)
Affinity DataKi:  428nM ΔG°:  -9.03kcal/mole IC50:  460nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed