BDBM35375 6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfanylmethyl)phenyl]carbonyl-3-methyl-1,4-dihydropyrido[2,3-d]pyrimidin-2-one::6-[5-chloro-2-hydroxy-3-(pyrimidin-2-ylsulfanylmethyl)benzoyl]-3-methyl-1,4-dihydropyrido[2,3-d]pyrimidin-2-one::6-[5-chloro-2-hydroxy-3-[(2-pyrimidylthio)methyl]benzoyl]-3-methyl-1,4-dihydropyrido[2,3-d]pyrimidin-2-one::6-[[5-chloro-2-hydroxy-3-[(2-pyrimidinylthio)methyl]phenyl]-oxomethyl]-3-methyl-1,4-dihydropyrido[2,3-d]pyrimidin-2-one::MLS000058022::SMR000063041::cid_2077850

SMILES CN1Cc2cc(cnc2NC1=O)C(=O)c1cc(Cl)cc(CSc2ncccn2)c1O

InChI Key InChIKey=ZTJNWWANFGWTCN-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 35375   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35375(6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfany...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35375(6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfany...)
Affinity DataIC50: >5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM35375(6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfany...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35375(6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfany...)
Affinity DataIC50: >1.10E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35375(6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfany...)
Affinity DataIC50:  1.26E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetEstrogen receptor(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM35375(6-[5-chloranyl-2-oxidanyl-3-(pyrimidin-2-ylsulfany...)
Affinity DataIC50: >5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay