BDBM35379 2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester::2-(2-furyl)cinchoninic acid [2-(6-amino-1-isobutyl-2,4-diketo-3-methyl-pyrimidin-5-yl)-2-keto-ethyl] ester::MLS000058168::SMR000063262::[2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxopyrimidin-5-yl]-2-oxoethyl] 2-(furan-2-yl)quinoline-4-carboxylate::[2-[4-azanyl-1-methyl-3-(2-methylpropyl)-2,6-bis(oxidanylidene)pyrimidin-5-yl]-2-oxidanylidene-ethyl] 2-(furan-2-yl)quinoline-4-carboxylate::cid_2094474

SMILES CC(C)Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccco2)c(=O)n(C)c1=O

InChI Key InChIKey=ABFGKTKVMVRAGW-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 35379   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  2.31E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  5.27E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  2.55E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  1.68E+4nMAssay Description:The MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay has been Developed and Run at the University of Pittsbur...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  1.31E+4nMAssay Description:The Cdc25B Phosphatase Secondary Selectivity Assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 Phosphatase Secondary Selectivity Assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  2.55E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  2.42E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50: >5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  5.81E+3nMAssay Description:LYP, a lymphocyte specific protein tyrosine phosphatase that plays a critical regulatory role in T cell receptor signaling, is encoded by the PTPN22 ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  4.66E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  2.59E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEstrogen receptor beta(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35379(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Affinity DataIC50:  5.00E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay