BDBM35383 MLS000091355::N-(4-methyl-5-oxidanylidene-chromeno[4,3-b]pyridin-2-yl)-4-pyrrolidin-1-ylsulfonyl-benzamide::N-(4-methyl-5-oxo-2-[1]benzopyrano[4,3-b]pyridinyl)-4-(1-pyrrolidinylsulfonyl)benzamide::N-(4-methyl-5-oxo-5H-chromeno[4,3-b]pyridin-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide::N-(4-methyl-5-oxochromeno[4,3-b]pyridin-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide::N-(5-keto-4-methyl-chromeno[4,3-b]pyridin-2-yl)-4-pyrrolidinosulfonyl-benzamide::SMR000025916::cid_3236129

SMILES Cc1cc(NC(=O)c2ccc(cc2)S(=O)(=O)N2CCCC2)nc2c3ccccc3oc(=O)c12

InChI Key InChIKey=JWGJCINPUPMGIM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 35383   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50:  3.82E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50:  2.61E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50:  2.61E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50: >5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35383(MLS000091355 | N-(4-methyl-5-oxidanylidene-chromen...)
Affinity DataIC50:  2.49E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay