BDBM35415 1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fluorophenyl)-5,7-dimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-1-propanone::1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fluorophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propan-1-one::1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fluorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl]propan-1-one::8-{3-[2-(3-fluorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl]propanoyl}-1,4-dioxa-8-azaspiro[4.5]decane::MLS000089608::SMR000027956::cid_3245990

SMILES Cc1nc2cc(nn2c(C)c1CCC(=O)N1CCC2(CC1)OCCO2)-c1cccc(F)c1

InChI Key InChIKey=NRPKNEXLHUETPF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 35415   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50:  1.27E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35415(1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-[2-(3-fl...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay