BDBM35489 1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2-yl)-urea::MLS000035450::N-[(3,4-dichloro-5-keto-2H-furan-2-yl)carbamoyl]acetamide::N-[(3,4-dichloro-5-oxo-2H-furan-2-yl)carbamoyl]acetamide::N-[[(3,4-dichloro-5-oxo-2H-furan-2-yl)amino]-oxomethyl]acetamide::N-[[3,4-bis(chloranyl)-5-oxidanylidene-2H-furan-2-yl]carbamoyl]ethanamide::SMR000001295::cid_654815

SMILES CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl

InChI Key InChIKey=NYALSNBKNBTFOV-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35489   

TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35489(1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...)
Affinity DataIC50:  2.12E+3nMpH: 6.8 T: 2°CAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM35489(1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProcathepsin L(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35489(1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35489(1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...)
Affinity DataIC50:  2.12E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay