BDBM35509 2-thiophenecarboxylic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester::5-amino-1-(4-methoxyphenylsulfonyl)-1H-pyrazol-3-yl thiophene-2-carboxylate::5-amino-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrazol-3-yl thiophene-2-carboxylate::CHEMBL243314::MLS000086044::SMR000021572::[5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] thiophene-2-carboxylate::[5-azanyl-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] thiophene-2-carboxylate::cid_3240114::thiophene-2-carboxylic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] ester

SMILES COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2cccs2)cc1N

InChI Key InChIKey=GASCXMZEQJQACK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 35509   

TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  1.16E+3nMpH: 6.8 T: 2°CAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  945nMAssay Description:Human liver cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease. There has been a recent resurgence of interest in cathepsin B due to research...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  692nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin G(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  2.52E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  110nMAssay Description:Inhibition of WNV NS2B-NS3 protease by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50: >5.00E+4nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  877nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCathepsin B(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM35509(2-thiophenecarboxylic acid [5-amino-1-(4-methoxyph...)
Affinity DataIC50:  110nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay