BDBM356617 N-{3-[7-(4-{2-[(2S)-2-(Hydroxymethyl)pyrrolidin-1-yl]-1-methyl-2-oxoethyl}phenyl)imidazo[1,2-b]pyridazin-3-yl]phenyl}-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 106::US10813930, Ex. No. 106
SMILES CC(C(=O)N1CCC[C@H]1CO)c1ccc(cc1)-c1cnn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1
InChI Key InChIKey=MAZMCAJZRNKAIJ-LUTIACGYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 356617
Affinity DataIC50: <10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair