BDBM365126 9-benzyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5- yl)amino)pyridin-4-yl)- 8,9-dihydro-1,2,2a1,6- tetraazabenzo[cd]azulen- 7(6H)-one::US10842799, I-61::US9867833, Compound I-61(S)

SMILES CN1c2cc(cc3nnc(C(Cc4ccccc4)CC1=O)n23)-c1ccnc(Nc2ccnn2C)c1

InChI Key InChIKey=FRGAEHIHCCSLPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 365126   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365126(9-benzyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5- y...)
Affinity DataIC50:  0.0730nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365126(9-benzyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5- y...)
Affinity DataIC50:  5.83nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent