BDBM365198 N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihydro- 7H-6-oxa-1,2,2a1- triazabenzo[cd]azulen-4- yl)pyridin-2-amine::US10278975, Compound I-103R::US10517878, Compound I-103::US10842799, I-103::US9867833, Compound I-103(S)

SMILES CCCC1CCOc2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)c1

InChI Key InChIKey=PNRRHHJLDFBADH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 365198   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365198(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihy...)
Affinity DataIC50:  2.77nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365198(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihy...)
Affinity DataIC50:  2.77nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365198(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihy...)
Affinity DataIC50:  2.77nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365198(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihy...)
Affinity DataIC50:  0.0260nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent