BDBM366124 US9873693, Compound 332::US9873693, Compound 47

SMILES Fc1ccc(Cn2cccc(C(=O)NCc3cccc(c3)-c3c[nH]c4ncc(cc34)-c3cccnc3)c2=O)cc1F

InChI Key InChIKey=UXBQYKWNFCTLDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 366124   

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366124(US9873693, Compound 332 | US9873693, Compound 47)
Affinity DataIC50: <500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-phosphoinositide-dependent protein kinase 1 [51-360](Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366124(US9873693, Compound 332 | US9873693, Compound 47)
Affinity DataIC50: <500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent