BDBM36897 8-fluoranyl-4-(4-phenylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole::8-fluoro-4-(4-phenyl-1-piperazinyl)-5H-pyrimido[5,4-b]indole::8-fluoro-4-(4-phenylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole::8-fluoro-4-(4-phenylpiperazino)-5H-pyrimid[5,4-b]indole::MLS000078400::SMR000040426::cid_659453

SMILES Fc1ccc2[nH]c3c(ncnc3c2c1)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=SYOWPIWWSKIYGB-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36897   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36897(8-fluoranyl-4-(4-phenylpiperazin-1-yl)-5H-pyrimido...)
Affinity DataEC50:  9.52E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36897(8-fluoranyl-4-(4-phenylpiperazin-1-yl)-5H-pyrimido...)
Affinity DataEC50:  1.85E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36897(8-fluoranyl-4-(4-phenylpiperazin-1-yl)-5H-pyrimido...)
Affinity DataIC50:  1.06E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36897(8-fluoranyl-4-(4-phenylpiperazin-1-yl)-5H-pyrimido...)
Affinity DataIC50:  1.23E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36897(8-fluoranyl-4-(4-phenylpiperazin-1-yl)-5H-pyrimido...)
Affinity DataEC50: >3.00E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay