BDBM36931 6-amino-1'-(4-chlorobenzyl)-2'-keto-3-methyl-spiro[2H-pyrano[2,3-c]pyrazole-4,3'-indoline]-5-carbonitrile::6-amino-1'-[(4-chlorophenyl)methyl]-3-methyl-2'-oxo-5-spiro[2H-pyrano[2,3-c]pyrazole-4,3'-indole]carbonitrile::6-amino-1'-[(4-chlorophenyl)methyl]-3-methyl-2'-oxospiro[2H-pyrano[2,3-c]pyrazole-4,3'-indole]-5-carbonitrile::6-azanyl-1'-[(4-chlorophenyl)methyl]-3-methyl-2'-oxidanylidene-spiro[2H-pyrano[2,3-c]pyrazole-4,3'-indole]-5-carbonitrile::MLS000082271::SMR000044710::cid_663934

SMILES Cc1[nH]nc2OC(=N)C(C#N)C3(C(=O)N(Cc4ccc(Cl)cc4)c4ccccc34)c12

InChI Key InChIKey=RHGREDIETPFGDU-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36931   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36931(6-amino-1'-(4-chlorobenzyl)-2'-keto-3-methyl-spiro...)
Affinity DataEC50:  4.36E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36931(6-amino-1'-(4-chlorobenzyl)-2'-keto-3-methyl-spiro...)
Affinity DataEC50:  5.80E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36931(6-amino-1'-(4-chlorobenzyl)-2'-keto-3-methyl-spiro...)
Affinity DataEC50: >3.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay