BDBM36953 3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiazole::3-(3,4-diethoxyphenyl)-5-pyridin-4-yl-1,2,4-oxadiazole::MLS000042464::SMR000047734::US10544136, Compound 257::cid_666359

SMILES CCOc1ccc(cc1OCC)-c1noc(n1)-c1ccncc1

InChI Key InChIKey=SDQKDGIXTOSJJL-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 36953   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36953(3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  428nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36953(3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  1.16E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Networ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36953(3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  7.30nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36953(3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  613nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36953(3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiaz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM36953(3-(3,4-diethoxyphenyl)-5-(4-pyridyl)-1,2,4-oxadiaz...)
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay