BDBM371100 US10239843, Example 207::US10239843, Example 285
SMILES Cc1cc(Cn2c(=O)n(Cc3cc(C)nn3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(C)CC2)on1
InChI Key InChIKey=SWIWJXUWGZZTFL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 371100
Affinity DataIC50: 38nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair