BDBM371476 N-[1-(Fluoromethyl)cyclopropyl]-1-(isoxazol-5-ylmethyl)-3-[(1-methylpyrazol-4-yl)methyl]-2,4-dioxo-quinazoline-6-sulfonamide::US10239843, Example 585

SMILES Cn1cc(Cn2c(=O)n(Cc3ccno3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)cn1

InChI Key InChIKey=RXNNACZMKOQDGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371476   

TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371476(N-[1-(Fluoromethyl)cyclopropyl]-1-(isoxazol-5-ylme...)
Affinity DataIC50:  38nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent