BDBM37539 7-(2-fluorobenzyl)-1,3-dimethyl-8-(piperonylamino)xanthine::8-(1,3-benzodioxol-5-ylmethylamino)-7-[(2-fluorophenyl)methyl]-1,3-dimethyl-purine-2,6-dione::8-(1,3-benzodioxol-5-ylmethylamino)-7-[(2-fluorophenyl)methyl]-1,3-dimethylpurine-2,6-dione::MLS000079182::SMR000038689::cid_657807

SMILES Cn1c2nc(NCc3ccc4OCOc4c3)n(Cc3ccccc3F)c2c(=O)n(C)c1=O

InChI Key InChIKey=GIBLGVWWFIPENH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37539   

TargetHuntingtin(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37539(7-(2-fluorobenzyl)-1,3-dimethyl-8-(piperonylamino)...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay