BDBM37553 5-(2-hydroxy-5-methyl-benzoyl)-2-keto-1-(tetrahydrofurfuryl)nicotinonitrile::5-(2-hydroxy-5-methylbenzoyl)-2-oxo-1-(oxolan-2-ylmethyl)pyridine-3-carbonitrile::5-(5-methyl-2-oxidanyl-phenyl)carbonyl-2-oxidanylidene-1-(oxolan-2-ylmethyl)pyridine-3-carbonitrile::5-[(2-hydroxy-5-methylphenyl)-oxomethyl]-2-oxo-1-(2-oxolanylmethyl)-3-pyridinecarbonitrile::MLS000056762::SMR000066362::cid_2998591

SMILES Cc1ccc(O)c(c1)C(=O)c1cc(C#N)c(=O)n(CC2CCCO2)c1

InChI Key InChIKey=ZVTAYUCZPGRYDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37553   

TargetHuntingtin(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37553(5-(2-hydroxy-5-methyl-benzoyl)-2-keto-1-(tetrahydr...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay