BDBM377249 US10265307, Example 72-2::US10517858, Example 72 (Diastereoisomer 2)::US10828290, Example 72 (Diastereoisomer 2)
SMILES CC(C)(O)c1cc(F)c(c(F)c1)-c1nc(ccc1F)C(=O)Nc1cnc2[C@H](O)CCc2c1N1C[C@@H](N)C[C@H](C1)C(F)(F)F
InChI Key InChIKey=BTEZDBVENXOPTN-ZCCHDVMBSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 377249
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.84 compound/DMSO in the assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.84 compound/DMSO in the assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-1 and Pim-3 kinase assays20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μcompound/DMSO in the assa...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-2 kinase assay-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay buffer (50 m...More data for this Ligand-Target Pair