BDBM377786 5-amino-1-(1-cyanopiperidin-3-yl)-3-[4-(2,4-difluorobenzyl)phenyl]-1H-pyrazole-4-carboxamide::US10266513, Example 80::US10266513, Example 81::US10266513, Example 82::US10815213, Example 82
SMILES NC(=O)c1c(N)n(nc1-c1ccc(Cc2ccc(F)cc2F)cc1)C1CCCN(C1)C#N
InChI Key InChIKey=GOFHOZWIENAJES-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 377786
Affinity DataIC50: 15.6nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Affinity DataIC50: 15.6nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair