BDBM377834 5-amino-1-{1-[(2E)-but-2-enoyl]piperidin-3-yl}-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 128::US10815213, Example 128

SMILES C\C=C\C(=O)N1CCCC(C1)n1nc(c(C(N)=O)c1N)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=RUWAHHLANQFDOG-FARCUNLSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 377834   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377834(5-amino-1-{1-[(2E)-but-2-enoyl]piperidin-3-yl}-3-(...)
Affinity DataIC50:  4.5nMAssay Description:BTK: TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377834(5-amino-1-{1-[(2E)-but-2-enoyl]piperidin-3-yl}-3-(...)
Affinity DataIC50:  4.5nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent