BDBM384120 1-(3-(2,3- Dichlorophenyl)-1H- pyrazolo[3,4-b]- pyrazin-6-yl)-N,4- dimethylpiperidin-4- amine::US10280171, Example 6::US10851110, Example 6::US11466017, Example 6
SMILES CNC1(C)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cccc(Cl)c1Cl
InChI Key InChIKey=MEDFNRZYVCVZEM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 384120
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: 2nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: 2nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataIC50: 2nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair