BDBM38892 (E)-1-(4-methylphenyl)-3-(2-pyridinylamino)-2-propen-1-one::(E)-1-(4-methylphenyl)-3-(pyridin-2-ylamino)prop-2-en-1-one::(E)-1-(p-tolyl)-3-(2-pyridylamino)prop-2-en-1-one::MLS000039305::SMR000040719::cid_1907983

SMILES Cc1ccc(cc1)C(=O)CC=Nc1ccccn1

InChI Key InChIKey=XVQXYWPCJZEZDN-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 38892   

TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38892((E)-1-(4-methylphenyl)-3-(2-pyridinylamino)-2-prop...)
Affinity DataIC50:  2.09E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38892((E)-1-(4-methylphenyl)-3-(2-pyridinylamino)-2-prop...)
Affinity DataIC50:  1.50E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM38892((E)-1-(4-methylphenyl)-3-(2-pyridinylamino)-2-prop...)
Affinity DataEC50:  4.24E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38892((E)-1-(4-methylphenyl)-3-(2-pyridinylamino)-2-prop...)
Affinity DataIC50: >1.10E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38892((E)-1-(4-methylphenyl)-3-(2-pyridinylamino)-2-prop...)
Affinity DataIC50:  1.04E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay