BDBM388967 4-[5-{[(3R)-1-(2- cyanoethyl)piperidin-3-yl]methoxy}- 8-(5-fluoro-6-methoxypyridin-3- yl)imidazo[1,2-c]pyrimidin-7- yl]benzonitrile::US10800779, Example 81::US11401272, Example 81::US9944647, Example 81
SMILES COc1ncc(cc1F)-c1c(nc(OC[C@@H]2CCCN(CCC#N)C2)n2ccnc12)-c1ccc(cc1)C#N
InChI Key InChIKey=VQGXSAFTJHRQPF-HXUWFJFHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 388967
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair