BDBM388997 US10800779, Example 106::US11401272, Example 106::US9944647, Example 106::methyl [5-(7-(4-cyanophenyl)-5- {[(3R)-1-methylpiperidin-3- yl]methoxy}imidazo[1,2- c]pyrimidin-8-yl)-2- methylphenyl]methylcarbamate

SMILES COC(=O)N(C)c1cc(ccc1C)-c1c(nc(OC[C@@H]2CCCN(C)C2)n2ccnc12)-c1ccc(cc1)C#N

InChI Key InChIKey=PKVJNKOZMNQSLL-JOCHJYFZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 388997   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388997(US10800779, Example 106 | US11401272, Example 106 ...)
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388997(US10800779, Example 106 | US11401272, Example 106 ...)
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388997(US10800779, Example 106 | US11401272, Example 106 ...)
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent