BDBM389026 4-[5-{[(3R)-1-(2-hydroxy-2- methylpropyl)piperidin-3- yl]methoxy}-8-(3-methyl-2-oxo-2,3- dihydro-1,3-benzoxazol-6- yl)imidazo[1,2-c]pyrimidin-7- yl]benzonitrile::US10800779, Example 135::US11401272, Example 135::US9944647, Example 135
SMILES Cn1c2ccc(cc2oc1=O)-c1c(nc(OC[C@@H]2CCCN(CC(C)(C)O)C2)n2ccnc12)-c1ccc(cc1)C#N
InChI Key InChIKey=CUAIVPPTLQBRGA-OAQYLSRUSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 389026
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair