BDBM392548 4-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)methyl)-7-((3- chloroquinolin-6-yl)methyl)-7H- pyrrolo[2,3-d]pyrimidine-5- carboxamide::US10301284, Example 34::US10781200, Example 34

SMILES Cc1cc(N)nc(C)c1CNC(=O)c1cn(Cc2ccc3ncc(Cl)cc3c2)c2ncnc(N)c12

InChI Key InChIKey=KGPFROBTQTWIBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392548   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392548(4-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392548(4-amino-N-((6-amino-2,4- dimethylpyridin-3-yl)meth...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent