BDBM392564 N-((3-chloro-1H-pyrrolo[2,3- b]pyridin-5-yl)methyl)-1-((3- chloroquinolin-6-yl)methyl)-3-cyano- 1H-pyrazole-4-carboxamide::US10301284, Example 50::US10781200, Example 50

SMILES Clc1c[nH]c2ncc(CNC(=O)c3cn(Cc4ccc5ncc(Cl)cc5c4)nc3C#N)cc12

InChI Key InChIKey=WUPSQPWFFJCKGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392564   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392564(N-((3-chloro-1H-pyrrolo[2,3- b]pyridin-5-yl)methyl...)
Affinity DataIC50:  550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392564(N-((3-chloro-1H-pyrrolo[2,3- b]pyridin-5-yl)methyl...)
Affinity DataIC50:  550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent