BDBM392569 N-((5-chloro-1H-indazol-3-yl)methyl)- 1-((3-chloro-8-fluoroquinolin-6- yl)methyl)-3-cyano-1H-pyrazole-4- carboxamide::US10301284, Example 55::US10781200, Example 55

SMILES Fc1cc(Cn2cc(C(=O)NCc3n[nH]c4ccc(Cl)cc34)c(n2)C#N)cc2cc(Cl)cnc12

InChI Key InChIKey=FZQKNWVIDPCNAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392569   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392569(N-((5-chloro-1H-indazol-3-yl)methyl)- 1-((3-chloro...)
Affinity DataIC50:  550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392569(N-((5-chloro-1H-indazol-3-yl)methyl)- 1-((3-chloro...)
Affinity DataIC50:  550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent