BDBM392644 N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-7-((3-chloroquinolin-6- yl)methyl)-4-methoxy-7H-pyrrolo[2,3- d]pyrimidine-5-carboxamide::US10301284, Example 131::US10781200, Example 131

SMILES COc1ncnc2n(Cc3ccc4ncc(Cl)cc4c3)cc(C(=O)NCc3c(C)cc(N)nc3C)c12

InChI Key InChIKey=CBZIOLZYDJEJLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392644   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392644(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-7-((...)
Affinity DataIC50:  550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392644(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-7-((...)
Affinity DataIC50:  550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent