BDBM392655 US10301284, Example 142::US10781200, Example 142::ethyl 3-(((6-amino-2,4- dimethylpyridin-3- yl)methyl)carbamoyl)-1-((3- chloroquinolin-6-yl)methyl)-1H-1,2,4- triazole-5-carboxylate

SMILES CCOC(=O)c1nc(nn1Cc1ccc2ncc(Cl)cc2c1)C(=O)NCc1c(C)cc(N)nc1C

InChI Key InChIKey=FCYBAWFLNBGASR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392655   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392655(US10301284, Example 142 | US10781200, Example 142 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392655(US10301284, Example 142 | US10781200, Example 142 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent