BDBM395359 US10308636, Example 44-6

SMILES OC(=O)c1cccc(OCC2CCN(CC2)c2ccc(cn2)-c2nc(c[nH]2)C(F)(F)F)c1Cl

InChI Key InChIKey=KOQSKAHQOHEJDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395359   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395359(US10308636, Example 44-6)
Affinity DataIC50:  0.780nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent