BDBM395624 2-((7-cyano-2-(3'- (5-(2-((R)-3- hydroxypyrrolidin- 1-yl)acetyl)-5,6- dihydro-4H-pyrrolo- [3,4-d]thiazol-2-yl)- 2,2'-dimethyl- biphenyl-3-yl)benzo- [d]oxazol-5-yl)- methyl)-2-azaspiro- [3.3]heptane-6- carboxylic acid::US10308644, Example 234::US10800768, Example 234::US11339149, Example 234
SMILES Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3s2)C(=O)CN2CC[C@@H](O)C2)c1C)-c1nc2cc(CN3CC4(CC(C4)C(O)=O)C3)cc(C#N)c2o1
InChI Key InChIKey=AGPGTTUMITYCLE-MUUNZHRXSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 395624
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent