BDBM399582 US10323036, Compound I-25::US10793574, Compound I-25
SMILES COc1c(Nc2cc(Nc3ccc(cn3)C#N)nc3[nH]n(C)c(=O)c23)cccc1-c1ncn(C)n1
InChI Key InChIKey=LEHWUVHCAPPDAL-UHFFFAOYSA-N
Data 2 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 399582
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: 0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: 0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair