BDBM399586 US10323036, Compound I-30::US10793574, Compound I-30
SMILES COc1c(Nc2cc(Nc3cccc(n3)C#N)nc3[nH]n(C)c(=O)c23)cccc1-c1ncn(C)n1
InChI Key InChIKey=WIORIHROMMDENI-UHFFFAOYSA-N
Data 2 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 399586
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair