BDBM399586 US10323036, Compound I-30::US10793574, Compound I-30

SMILES COc1c(Nc2cc(Nc3cccc(n3)C#N)nc3[nH]n(C)c(=O)c23)cccc1-c1ncn(C)n1

InChI Key InChIKey=WIORIHROMMDENI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 399586   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM399586(US10323036, Compound I-30 | US10793574, Compound I...)
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM399586(US10323036, Compound I-30 | US10793574, Compound I...)
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent