BDBM400067 (R)-7-(2-((1-(1H-1,2,3-triazol-4-yl)cyclopropyl)amino)-2-oxoacetyl)-N-(3-chloro-4-fluorophenyl)-2-fluoro-6-methyl-2,3-dihydro-1H-pyrrolizine carboxamide ::US10328053, Compound 45::US10874640, Compound 45

SMILES Cc1c(C(=O)C(=O)NC2(CC2)c2c[nH]nn2)c2C[C@@H](F)Cn2c1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 400067   

TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Gilead Sciences

US Patent
LigandPNGBDBM400067((R)-7-(2-((1-(1H-1,2,3-triazol-4-yl)cyclopropyl)am...)
Affinity DataEC50:  9.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400067((R)-7-(2-((1-(1H-1,2,3-triazol-4-yl)cyclopropyl)am...)
Affinity DataEC50:  9.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent